Anti-Cancer Effect of Metabotropic Glutamate Receptor 1 Inhibition in Human Glioma U87 Cells: Involvement of PI3K/Akt/mTOR Pathway
Background: Metabotropic glutamate receptors (mGluRs) are MCT Oil G-protein-coupled receptors that mediate neuronal excitability and synaptic plasticity in the central nervous system, and emerging evidence suggests a role of mGluRs in the biology of cancer.Previous studies showed that mGluR1 was a potential therapeutic target for the treatment of b